Silybum marianum: not Just Silymarin and Flavonolignans-
نویسندگان
چکیده
منابع مشابه
Antioxidant Activity of Hepatoprotective Silymarin and Silybum marianum L. Extract
The paper presents the antioxidant activity evaluation of Silybum marianum L. extract in comparison with the commercial silymarin standard solution (2 mg/mL) and the time-dependent antioxidant capacity by calculating the free radical 2,2-diphenyl-1-pycryl-hydrazyl (DPPH) reaction rate in the presence of these biosystems. The best result was obtained in the case of S. marianum L. extract, with a...
متن کاملMilk Thistle (Silybum marianum)
Milk thistle is a well known and commonly used herb, used particularly in hepatic diseases. It has very potent antioxidant, anti-inflammatory, and antifibrotic properties (1). As a single agent its therapeutic effects in liver disease appear to be modest (2,3,4,5). Herbal medicines and supplements are likely to be much more beneficial when used synergistically in combinations or formulas. Milk ...
متن کاملSilybum Marianum for Diabetes
H. Fallah Huseini*, B. Larijani, R. Heshmat, H. Fakhrzadeh, B. Radjabipour, T. Toliat and Mohsin Raza Department of Pharmacology, Institute of Medicinal Plants, ACECR Tehran, Iran Endocrinology and Metabolism Research Center, Tehran University of Medical Sciences, Tehran, Iran School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran Department of Physiology, School of Medical Sci...
متن کاملTwo flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
Milk thistle (Silybum marianum) is a popular herbal product used for hepatoprotection and chemoprevention. Two commercially available formulations are the crude extract, silymarin, and the semipurified product, silibinin. Silymarin consists of at least seven flavonolignans, of which the most prevalent are the diastereoisomers silybin A and silybin B; silibinin consists only of silybin A and sil...
متن کاملFlavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum).
Silybin A (1), silybin B (2), and isosilybin A (3), three of the seven flavonolignans that constitute silymarin, an extract of the fruits of milk thistle (Silybum marianum), were detected for the first time from a fungal endophyte, Aspergillus iizukae, isolated from the surface-sterilized leaves of S. marianum. The flavonolignans were identified using a UPLC-PDA-HRMS-MS/MS method by matching re...
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ژورنال
عنوان ژورنال: Records of Natural Products
سال: 2021
ISSN: 1307-6167
DOI: 10.25135/rnp.219.20.09.1827